About RVIS (Residual Variation Intolerance Score) is a gene score based module intended to help in the interpretation of human sequence data.
News We now provide a revised RVIS gene score (unpublished) based on the recently released ExAC sequencing data. The ExAC data can be found at (exac.broadinstitute.org).
Examples - Gene: SCN1A, Gene list: SCN1A, ATP1A3, HLA-A, MTOR, MUC5B (comma delimited), All.Gene
| GENE | RVIS | %OEratio | %ExAC_OEratio | ExAC_LoF_FDR | %ExAC_RVIS |
|---|---|---|---|---|---|
| CNTN1 | -1.06 (7.48%) | NA | 29.32522124% | 2.6054E-09 | 12.82% |
Click Here to download the full list of CCDS Release 9 RVIS gene score. Please cite doi: 10.1371/journal.pgen.1003709
Click Here to download novel unpublished RVIS gene score based on ExAC sequencing data release (accessed: January 13th 2015 [updated scores for release0.3]).
